Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30285730 | 1.00 | HTT (0.44) | HTTTP53MAPTALDH1A1LMNA | |
| SCHEMBL29005576 | 0.88 | TP53 (0.42) | HTTTP53MAPTALDH1A1LMNA | |
| SCHEMBL29005420 | 0.85 | SNCA (0.36) | HTTTP53MAPTALDH1A1LMNA | |
| SCHEMBL30285631 | 0.85 | SNCA (0.36) | HTTTP53MAPTALDH1A1LMNA | |
| SCHEMBL30285745 | 0.85 | TP53 (0.47) | HTTTP53MAPTALDH1A1LMNA | |
| SCHEMBL30285884 | 0.85 | ALDH1A1 (0.46) | HTTTP53MAPTALDH1A1LMNA | |
| SCHEMBL29005482 | 0.85 | ALDH1A1 (0.46) | HTTTP53MAPTALDH1A1LMNA | |
| SCHEMBL30285811 | 0.85 | MEN1 (0.45) | HTTTP53MAPTALDH1A1LMNA | |
| SCHEMBL29005766 | 0.85 | MEN1 (0.45) | HTTTP53MAPTALDH1A1LMNA | |
| SCHEMBL29005567 | 0.83 | KMT2A (0.38) | HTTTP53MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |