Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | PYGM | P11217 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30285721 | 1.00 | TP53 (0.36) | TP53ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL29005432 | 0.92 | TP53 (0.40) | TP53ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL29005468 | 0.84 | ALDH1A1 (0.45) | TP53ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL30285631 | 0.84 | SNCA (0.36) | TP53ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL29005420 | 0.84 | SNCA (0.36) | TP53ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL30285840 | 0.84 | TSHR (0.40) | TP53ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL30285811 | 0.84 | MEN1 (0.45) | TP53ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL29005766 | 0.84 | MEN1 (0.45) | TP53ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL30285884 | 0.84 | ALDH1A1 (0.46) | TP53ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29005482 | 0.84 | ALDH1A1 (0.46) | TP53ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |