Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 8/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361218 | 1.00 | CRHR1 (0.35) | CRHR1TRPM8PKMCACNA1BAPBA1 | |
| SCHEMBL25027558 | 0.75 | CRHR1 (0.35) | CRHR1TRPM8 | |
| SCHEMBL10072452 | 0.71 | LRRK2 (0.44) | TRPM8 | |
| SCHEMBL26789545 | 0.68 | LRRK2 (0.33) | CRHR1 | |
| SCHEMBL6082899 | 0.64 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL23211566 | 0.64 | HCRTR2 (0.40) | CRHR1PKMCACNA1BAPBA1 | |
| SCHEMBL6168593 | 0.64 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL4777192 | 0.64 | — | — | |
| SCHEMBL4366842 | 0.63 | UTS2R (0.39) | — | |
| SCHEMBL839298 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996926-A | Indole compounds as androgen receptor modulators | 尼多生物科学有限公司 | 2023-04-21 | — | — | CN | disclosed |