SCHEMBL29005605

SCHEMBL29005605

CC(C)(C)c1ccc(Br)s1.N#CCC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.39
KMT2A Q03164 1/20 0.39
DAO P14920 1/20 0.36
YEATS4 O95619 1/20 0.34
GSK3B P49841 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33
CTSS P25774 1/20 0.33
RXFP1 Q9HBX9 3/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
GRIA4 P48058 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1773654 0.76 MAPK1 (0.38) MAPK1KMT2ADAOYEATS4GSK3B
SCHEMBL2087852 0.73 YEATS4 (0.46) MAPK1KMT2ADAOYEATS4GSK3B
SCHEMBL1492685 0.70 DAO (0.45) MAPK1KMT2ADAOGSK3BCES2
SCHEMBL1819000 0.68 DAO (0.44) MAPK1KMT2ADAOGSK3BCES2
SCHEMBL31283735 0.68 DAO (0.44) MAPK1KMT2ADAOGSK3BCES2
SCHEMBL16099474 0.68 DAO (0.44) MAPK1KMT2ADAOGSK3BCES2
SCHEMBL1818997 0.68 DAO (0.44) MAPK1KMT2ADAOGSK3BCES2
SCHEMBL1426699 0.67 GSK3B (0.61) KMT2ADAOGSK3BCES2CES1
Methyl Alcohol SCHEMBL27928369 0.65
Ethane SCHEMBL621831 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907383-B Di (benzopyrrole) phenothiazine organic dye, and preparation method and application thereof 华南理工大学 2023-05-23 CN disclosed