Sugi Predict

Sugi Predict / Targets / YEATS4

YEATS4

YEATS domain-containing protein 4 · O95619 · YEATS4 on Sugi Atlas →

1,022 patent compounds predicted against YEATS4, 568 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL4439903 SCHEMBL4439903 0.52 3/20
SCHEMBL4440180 SCHEMBL4440180 0.42 3/20
SCHEMBL14046580 SCHEMBL14046580 0.40 3/20
SCHEMBL2337922 SCHEMBL2337922 0.39 3/20
SCHEMBL15627653 SCHEMBL15627653 0.38 3/20
SCHEMBL15627829 SCHEMBL15627829 0.38 3/20
SCHEMBL15627982 SCHEMBL15627982 0.37 3/20
SCHEMBL17152309 SCHEMBL17152309 0.37 3/20
SCHEMBL15627654 SCHEMBL15627654 0.37 3/20
SCHEMBL17152168 SCHEMBL17152168 0.37 3/20
SCHEMBL4446497 SCHEMBL4446497 1.00 2/20
SCHEMBL4436922 SCHEMBL4436922 0.75 2/20
SCHEMBL5006614 SCHEMBL5006614 0.69 2/20
SCHEMBL24188452 SCHEMBL24188452 0.68 2/20
SCHEMBL4434784 SCHEMBL4434784 0.68 2/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL4445757) 0.67 2/20
SCHEMBL14008572 SCHEMBL14008572 0.66 2/20
SCHEMBL14146550 SCHEMBL14146550 0.65 2/20
SCHEMBL4437923 SCHEMBL4437923 0.62 2/20
SCHEMBL4446707 SCHEMBL4446707 0.62 2/20

Clinical trials — most relevant to YEATS4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Impact of tdrd9 Gene Mutations in the Therapeutic Response to L-carnitine in Oligoasthenozoospermic Men PHASE3ACTIVE_NOT_RECRUITING
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
NY-ESO-1 Protein With Montanide and CpG 7909 as Cancer Vaccine in Several Tumors PHASE1COMPLETED
Genomic Predictors of Recurrent Pregnancy Loss nanRECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Biomarkers in Samples of Bone Marrow From Patients With Acute Myeloid Leukemia nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Using Mobile Technology to Improve Self-Regulation nanCOMPLETED
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING
Elucidating the Molecular and Biochemical Basis of the Human AhR-mutation Disease nanUNKNOWN
Family Blood Pressure Program - HyperGEN nanCOMPLETED
Patient's Derived Organoids for Drug Screening in Glioblastoma nanNOT_YET_RECRUITING
Autophagy Bladder Cancer nanUNKNOWN
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Efficacy of Cognitive Rehabilitation Using Virtual Reality and Computer-based Cognitive Stimulation on Cognitive Impairment Associated to Movement Disorders nanCOMPLETED
Stress and Treatment Response in Puerto Rican Children With Asthma nanCOMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Family Blood Pressure Program - GENOA nanCOMPLETED
Family Blood Pressure Program - SAPPHIRe Network nanCOMPLETED
Molecular Epidemiology of Essential Hypertension nanCOMPLETED
Family Blood Pressure Program - GenNet Network nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
PCM1-JAK2 in Therapy Related Neoplasms nanUNKNOWN
Na+ Channel mRNA Regulation in Heart Failure nanCOMPLETED
Diet, Genetics, and CVD Risk Factor Response in Blacks nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
mTORC1 and Autophagy in Human Brown Adipocytes nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a YEATS4 binder may also engage these)

ProteinNameSimilarity
Q9CR11 — 1.000 Q9CR11 →
Q5U2U0 — 0.948 Q5U2U0 →
Q5ZIA5 — 0.947 Q5ZIA5 →
Q2KJ46 — 0.947 Q2KJ46 →
PSMD3 26S proteasome non-ATPase regulatory subunit 3 0.946 landscape →
Q9ESX5 — 0.946 Q9ESX5 →
Q5R922 — 0.946 Q5R922 →
Q5ZJH9 — 0.946 Q5ZJH9 →
D2SW95 — 0.945 D2SW95 →
COPB1 Coatomer subunit beta 0.945 landscape →
O60879 — 0.945 O60879 →
Q7QG73 — 0.945 Q7QG73 →
Q9JHS4 — 0.945 Q9JHS4 →
Q9JIF7 — 0.944 Q9JIF7 →
O82793 — 0.944 O82793 →
P23514 — 0.944 P23514 →
Q9NZI7 — 0.944 Q9NZI7 →
PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 0.944 landscape →
Q9Y5W8 — 0.943 Q9Y5W8 →
A0JN39 — 0.943 A0JN39 →
Q6PHS6 — 0.943 Q6PHS6 →
Q3ZBD9 — 0.943 Q3ZBD9 →
Q5RB16 — 0.943 Q5RB16 →
Q61166 — 0.942 Q61166 →
Q93V56 — 0.942 Q93V56 →
Q66HV4 — 0.942 Q66HV4 →
O48556 — 0.942 O48556 →
Q9BTC8 — 0.942 Q9BTC8 →
Q5R7N3 — 0.942 Q5R7N3 →
Q5XIY6 — 0.941 Q5XIY6 →