Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 11/20 | 0.47 |
| ▸ | CCNK | O75909 | 11/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.47 |
| ▸ | CDK2 | P24941 | 11/20 | 0.47 |
| ▸ | CDK9 | P50750 | 11/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 11/20 | 0.47 |
| ▸ | CDK7 | P50613 | 9/20 | 0.43 |
| ▸ | CCNH | P51946 | 9/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.43 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | NRAS | P01111 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028688 | 0.95 | CCNT1 (0.50) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL29364048 | 0.87 | CCNT1 (0.51) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL25028686 | 0.87 | CCNT1 (0.51) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL25027643 | 0.87 | CCNT1 (0.51) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL29364484 | 0.83 | CCNK (0.51) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL25028884 | 0.83 | CCNK (0.51) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL29361385 | 0.83 | CCNT1 (0.53) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL25028778 | 0.83 | CCNT1 (0.53) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL26719282 | 0.81 | DYRK1A (0.40) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL26717538 | 0.80 | CCNT1 (0.43) | CCNT1CCNKCCNE1CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| CN-115996926-A | Indole compounds as androgen receptor modulators | 尼多生物科学有限公司 | 2023-04-21 | — | — | CN | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |