Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CCNK | O75909 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 11/20 | 0.37 |
| ▸ | JAK3 | P52333 | 10/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | CDK7 | P50613 | 2/20 | 0.33 |
| ▸ | CCNH | P51946 | 2/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028688 | 0.85 | CCNT1 (0.50) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| SCHEMBL26719608 | 0.83 | JAK3 (0.43) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| Formic Acid SCHEMBL29005614 | 0.81 | CCNT1 (0.47) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| SCHEMBL26716959 | 0.80 | DYRK1A (0.40) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| SCHEMBL26718632 | 0.80 | DYRK1A (0.41) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| SCHEMBL25027651 | 0.80 | JAK3 (0.47) | CCNKCDK12JAK2JAK3 | |
| SCHEMBL29364416 | 0.80 | JAK3 (0.47) | CCNKCDK12JAK2JAK3 | |
| SCHEMBL25027523 | 0.80 | JAK3 (0.47) | CCNKCDK12JAK2JAK3 | |
| SCHEMBL29363962 | 0.80 | JAK3 (0.47) | CCNKCDK12JAK2JAK3 | |
| SCHEMBL25028660 | 0.80 | JAK3 (0.47) | CCNKCDK12JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | DYRK1A 1097/4885GSK3B 441/4885NFATC1 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.