SCHEMBL29006295

SCHEMBL29006295

CCCCC=Cc1nccn1CC

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42
TLR8 Q9NR97 2/20 0.40
ADORA3 P0DMS8 2/20 0.32
ADORA1 P30542 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29006278 0.95 TLR8 (0.42) ALDH1A1POLBKMT2ATLR8
SCHEMBL29058195 0.83 TLR8 (0.51) ALDH1A1POLBKMT2ATLR8
SCHEMBL23367993 0.82 KMT2A (0.35) ALDH1A1POLBKMT2ATLR8MAPT
SCHEMBL9069375 0.79 TLR8 (0.41) ALDH1A1POLBKMT2ATLR8
Hydrochloric Acid SCHEMBL1628074 0.78 TLR8 (0.42) ALDH1A1POLBKMT2ATLR8
Water SCHEMBL3401807 0.78 TLR8 (0.40) ALDH1A1POLBKMT2ATLR8
SCHEMBL28582151 0.77 KMT2A (0.36) ALDH1A1POLBKMT2ATLR8MAPT
SCHEMBL15901322 0.76 POLB (0.46) POLBKMT2A
SCHEMBL29006290 0.75 MGLL (0.41) ALDH1A1POLBKMT2ATLR8
SCHEMBL29006302 0.75 MGLL (0.41) ALDH1A1POLBKMT2ATLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178174-A Method for purifying hexamethylenediamine with low energy consumption 万华化学集团股份有限公司 2023-05-30 CN disclosed