SCHEMBL29006378

SCHEMBL29006378

CC1(C)c2ccccc2-c2ccc(OC=O)cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 16/20 0.40
PGR P06401 1/20 0.38
MLNR O43193 1/20 0.36
NR1I2 O75469 1/20 0.36
CHRM2 P08172 1/20 0.36
ADRB1 P08588 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
CHRM1 P11229 1/20 0.36
DRD2 P14416 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
CHRM3 P20309 1/20 0.36
DRD1 P21728 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29048685 0.80 MAPT (0.39)
SCHEMBL12393746 0.80 PDK2 (0.59) PDK2PGR
SCHEMBL29853561 0.80 PDK2 (0.59) PDK2PGR
SCHEMBL244275 0.77 PDK2 (0.42) PDK2PGR
SCHEMBL13168711 0.76 PDK2 (0.39) PDK2PGR
SCHEMBL3557265 0.75 PDK2 (0.41) PDK2PGRMLNRNR1I2CHRM2
SCHEMBL29924351 0.74 PDK2 (0.43) PDK2
SCHEMBL9916949 0.74 PDK2 (0.43) PDK2
SCHEMBL12306559 0.74 MAOA (0.50) PDK2
SCHEMBL5551776 0.74 PDK2 (0.43) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117321039-A Organic compound and organic light emitting device comprising the same 材料科学有限公司 2023-12-29 CN disclosed
CN-116156929-A Organic electroluminescent element 索路思高新材料有限公司 2023-05-23 CN disclosed