Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL1700914 | 1.00 | TP53 (0.85) | — | |
| Lactic Acid SCHEMBL28569436 | 0.96 | TP53 (0.92) | — | |
| Lactic Acid SCHEMBL4350607 | 0.96 | TP53 (0.92) | — | |
| L-Lactic Acid SCHEMBL29408581 | 0.96 | TP53 (0.92) | — | |
| Lactic Acid SCHEMBL838896 | 0.96 | — | — | |
| Lactic Acid SCHEMBL248090 | 0.96 | — | — | |
| L-Lactic Acid SCHEMBL5921449 | 0.96 | — | — | |
| Lactic Acid SCHEMBL2838779 | 0.96 | — | — | |
| L-Lactic Acid SCHEMBL5921377 | 0.96 | TP53 (0.92) | — | |
| Lactic Acid SCHEMBL3776949 | 0.96 | TP53 (0.92) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115998767-A | Application of manganese metal in preparation of medicines for treating, preventing or improving depression | 广东药科大学 | 2023-04-25 | — | — | CN | disclosed |