Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL28569436 | 1.00 | TP53 (0.92) | TP53TSHROR51E2SLC7A5ALDH1A1 | |
| Lactic Acid SCHEMBL3776949 | 1.00 | TP53 (0.92) | TP53TSHROR51E2SLC7A5ALDH1A1 | |
| Lactic Acid SCHEMBL4350607 | 1.00 | TP53 (0.92) | TP53TSHROR51E2SLC7A5ALDH1A1 | |
| Lactic Acid SCHEMBL838896 | 1.00 | — | — | |
| Lactic Acid SCHEMBL248090 | 1.00 | — | — | |
| D-Lactic Acid SCHEMBL29408597 | 1.00 | TP53 (0.92) | TP53TSHROR51E2SLC7A5ALDH1A1 | |
| L-Lactic Acid SCHEMBL5921449 | 1.00 | — | — | |
| Lactic Acid SCHEMBL2838779 | 1.00 | — | — | |
| L-Lactic Acid SCHEMBL5921377 | 1.00 | TP53 (0.92) | TP53TSHROR51E2SLC7A5ALDH1A1 | |
| Lactic Acid SCHEMBL969329 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240122855-A1 | Methods for the preparation of biologically active compounds in nanoparticulate form | ICEUTICA PTY LTD. (AU) | 2024-04-18 | — | — | US | disclosed |
| US-20220054418-A1 | Methods for the preparation of biologically active compounds in nanoparticulate form | ICEUTICA PTY LTD. (AU) | 2022-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220054418-A1 | Methods for the preparation of biologically active compounds in nanoparticulate form | ALPP, ALPG, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | TP53 57/4885TSHR 4055/4885OR51E2 4157/4885 |
| US-20240122855-A1 | Methods for the preparation of biologically active compounds in nanoparticulate form | ALPP, ALPG, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | TP53 57/4885TSHR 4055/4885OR51E2 4157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.