Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.47 |
| ▸ | PRKACA | P17612 | 3/20 | 0.47 |
| ▸ | PRKX | P51817 | 3/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.47 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.47 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.37 |
| ▸ | ACVR1B | P36896 | 3/20 | 0.37 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30254824 | 0.80 | ROCK2 (0.70) | ROCK2PRKACAPRKXROCK1PRKG1 | |
| SCHEMBL25406963 | 0.80 | ROCK2 (0.70) | ROCK2PRKACAPRKXROCK1PRKG1 | |
| SCHEMBL6192171 | 0.74 | ACACB (0.45) | CYP3A4SLC6A3 | |
| SCHEMBL6192176 | 0.74 | ACACB (0.45) | CYP3A4SLC6A3 | |
| SCHEMBL30341563 | 0.70 | MAPK1 (0.59) | ROCK2PRKACAPRKXROCK1PRKG1 | |
| SCHEMBL25405435 | 0.70 | MAPK1 (0.59) | ROCK2PRKACAPRKXROCK1PRKG1 | |
| SCHEMBL25408522 | 0.70 | MAPK1 (0.40) | ROCK2PRKACAPRKXROCK1PRKG1 | |
| SCHEMBL24568249 | 0.70 | PREP (0.55) | ROCK2PRKACAPRKXROCK1PRKG1 | |
| SCHEMBL25405218 | 0.69 | ROCK2 (0.56) | ROCK2PRKACAPRKXROCK1PRKG1 | |
| SCHEMBL25407462 | 0.69 | ROCK2 (0.56) | ROCK2PRKACAPRKXROCK1PRKG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157397-A | Heterocyclylpyridines as novel fungicides | 拜耳公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-4161914-A1 | HETEROCYCLYL PYRIDINES AS NOVEL FUNGICIDES | Bayer Aktiengesellschaft (DE) | 2023-04-12 | — | — | EP | disclosed |