SCHEMBL29007243

SCHEMBL29007243

c1ccc(COCc2cccc(COCc3ccccc3)c2)cc1

nearest known ligand 0.79

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.79
IDO1 P14902 1/20 0.50
AGXT P21549 2/20 0.48
MAOB P27338 3/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA7 P43166 2/20 0.45
CA9 Q16790 2/20 0.45
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.45
APP P05067 1/20 0.45
MAPT P10636 1/20 0.45
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
DAO P14920 1/20 0.44
TACR1 P25103 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5311581 0.89 TSHR (1.00) TSHRIDO1AGXTCA1CA2
Benzene SCHEMBL27997624 0.89 TSHR (1.00) TSHRIDO1AGXTCA1CA2
SCHEMBL27380 0.89 TSHR (1.00) TSHRIDO1AGXTCA1CA2
SCHEMBL6666825 0.88 TSHR (0.61) TSHRIDO1AGXTTACR1
SCHEMBL9491202 0.86 TSHR (0.94) TSHRIDO1AGXTCA1CA2
Methane SCHEMBL11192510 0.86 TSHR (0.94) TSHRIDO1AGXTCA1CA2
Water SCHEMBL15535487 0.86 TSHR (0.94) TSHRIDO1AGXTMAOBCA1
Calcium SCHEMBL2864550 0.86 TSHR (0.94) TSHRIDO1AGXTCA1CA2
SCHEMBL1009266 0.86 TSHR (0.94) TSHRIDO1AGXTCA1CA2
SCHEMBL9795394 0.86 TSHR (0.94) TSHRIDO1AGXTMAOBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114984933-A Dendritic organic small molecule gel silicon-based stationary phase material based on benzyl ether and preparation method thereof 宁夏大学 2022-09-02 CN claimed
CN-114984933-A Dendritic organic small molecule gel silicon-based stationary phase material based on benzyl ether and preparation method thereof 宁夏大学 2022-09-02 CN disclosed