Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | SYK | P43405 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30390144 | 0.87 | MEN1 (0.53) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL5999845 | 0.86 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL30389997 | 0.86 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL30389930 | 0.85 | SYK (0.67) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL29007317 | 0.85 | SYK (0.51) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL29007310 | 0.84 | SYK (0.50) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL29007284 | 0.84 | SYK (0.50) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL29007306 | 0.84 | SYK (0.50) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL30390002 | 0.81 | SYK (0.55) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL29007301 | 0.81 | NPC1 (0.56) | MEN1KMT2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960046-A | Preparation method of 1-amino substituted isoquinoline substances | 温州大学 | 2023-04-14 | — | — | CN | disclosed |