Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30389997 | 1.00 | MEN1 (0.56) | MEN1KMT2ASYKTDP1L3MBTL1 | |
| SCHEMBL30390144 | 0.96 | MEN1 (0.53) | MEN1KMT2ASYKTDP1L3MBTL1 | |
| SCHEMBL30389930 | 0.88 | SYK (0.67) | MEN1KMT2ASYKTDP1L3MBTL1 | |
| SCHEMBL29007317 | 0.88 | SYK (0.51) | MEN1KMT2ASYKTDP1L3MBTL1 | |
| SCHEMBL30390002 | 0.87 | SYK (0.55) | MEN1KMT2ASYKTDP1L3MBTL1 | |
| SCHEMBL29007284 | 0.86 | SYK (0.50) | MEN1KMT2ASYKTDP1L3MBTL1 | |
| SCHEMBL29007302 | 0.86 | MEN1 (0.53) | MEN1KMT2ASYKTDP1L3MBTL1 | |
| SCHEMBL29007310 | 0.86 | SYK (0.50) | MEN1KMT2ASYKTDP1L3MBTL1 | |
| SCHEMBL29007306 | 0.86 | SYK (0.50) | MEN1KMT2ASYKCYP1A2CYP3A4 | |
| SCHEMBL29007305 | 0.85 | SYK (0.43) | MEN1KMT2ASYKADORA2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960046-A | Preparation method of 1-amino substituted isoquinoline substances | 温州大学 | 2023-04-14 | — | — | CN | disclosed |
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | MEN1 2168/4885KMT2A 3343/4885SYK 3812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.