Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.39 |
| ▸ | MELK | Q14680 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30181041 | 1.00 | LMNA (0.43) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29007745 | 0.93 | LMNA (0.48) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30181102 | 0.89 | NPC1 (0.45) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29007911 | 0.89 | NPC1 (0.45) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL31024942 | 0.87 | LMNA (0.43) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30416714 | 0.87 | LMNA (0.45) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29007927 | 0.83 | LMNA (0.38) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30181201 | 0.83 | LMNA (0.38) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30416962 | 0.83 | MAPK8 (0.42) | LMNAMEN1KMT2AKDM4EMAPK8 | |
| SCHEMBL31157557 | 0.82 | LMNA (0.38) | LMNAMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157392-A | Compounds targeting RNA binding proteins or RNA modification proteins | 雷多纳治疗公司 | 2023-05-23 | — | — | CN | disclosed |