Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30181156 | 1.00 | CSF1R (0.41) | CSF1RNPC1MAPTALDH1A1LMNA | |
| SCHEMBL29007911 | 0.85 | NPC1 (0.45) | NPC1MAPTALDH1A1LMNAHPGD | |
| SCHEMBL30181102 | 0.85 | NPC1 (0.45) | NPC1MAPTALDH1A1LMNAHPGD | |
| SCHEMBL30417566 | 0.84 | ELANE (0.46) | CSF1RLMNAKMT2AMEN1KCNH2 | |
| SCHEMBL30417628 | 0.82 | MAPK8 (0.39) | CSF1RNPC1MAPTALDH1A1LMNA | |
| SCHEMBL29007976 | 0.80 | NPC1 (0.41) | CSF1RNPC1MAPTALDH1A1LMNA | |
| SCHEMBL30181266 | 0.80 | NPC1 (0.41) | CSF1RNPC1MAPTALDH1A1LMNA | |
| SCHEMBL30181171 | 0.79 | NPC1 (0.40) | CSF1RNPC1MAPTALDH1A1LMNA | |
| SCHEMBL30181075 | 0.77 | NPC1 (0.44) | CSF1RNPC1MAPTALDH1A1LMNA | |
| SCHEMBL30954831 | 0.75 | CSF1R (0.41) | CSF1RNPC1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157392-A | Compounds targeting RNA binding proteins or RNA modification proteins | 雷多纳治疗公司 | 2023-05-23 | — | — | CN | disclosed |