Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.37 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30181265 | 0.79 | ALDH1A1 (0.42) | NPC1CSF1RALDH1A1LMNAMAPT | |
| SCHEMBL29007909 | 0.79 | ALDH1A1 (0.42) | NPC1CSF1RALDH1A1LMNAMAPT | |
| SCHEMBL30417762 | 0.79 | ALDH1A1 (0.42) | NPC1CSF1RALDH1A1LMNAMAPT | |
| SCHEMBL29980044 | 0.79 | ALDH1A1 (0.45) | NPC1ALDH1A1LMNAMAPTBAZ2B | |
| SCHEMBL19971528 | 0.79 | ALDH1A1 (0.45) | NPC1ALDH1A1LMNAMAPTBAZ2B | |
| SCHEMBL10473152 | 0.77 | ADRB2 (0.44) | NPC1ALDH1A1LMNAMAPTBAZ2B | |
| SCHEMBL30297987 | 0.77 | CSF1R (0.41) | NPC1CSF1RALDH1A1LMNAMAPT | |
| SCHEMBL30954831 | 0.77 | CSF1R (0.41) | NPC1CSF1RALDH1A1LMNAMAPT | |
| SCHEMBL30181156 | 0.77 | CSF1R (0.41) | NPC1CSF1RALDH1A1LMNAMAPT | |
| SCHEMBL29007900 | 0.77 | CSF1R (0.41) | NPC1CSF1RALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157392-A | Compounds targeting RNA binding proteins or RNA modification proteins | 雷多纳治疗公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-4114831-A1 | COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS | Twentyeight-Seven, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |