⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418619 | 0.66 | SORD (0.50) | — | |
| SCHEMBL9803609 | 0.62 | SORD (0.43) | — | |
| SCHEMBL10168488 | 0.61 | KCNH2 (0.33) | — | |
| SCHEMBL3192090 | 0.61 | SORD (0.42) | — | |
| SCHEMBL724177 | 0.61 | SORD (0.42) | — | |
| SCHEMBL14536064 | 0.60 | NPC1 (0.41) | — | |
| SCHEMBL9382328 | 0.58 | GAA (0.36) | — | |
| SCHEMBL28913371 | 0.57 | — | — | |
| SCHEMBL28649087 | 0.57 | — | — | |
| SCHEMBL28629659 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952299-B | Fluorohydroxyproline derivatives for the preparation of protein degradation targeting chimeras | 邓迪大学 | 2023-04-18 | — | — | CN | disclosed |