Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24913825 | 0.74 | SMARCA2 (0.39) | SMARCA2SMARCA4PBRM1CHRM2CHRM4 | |
| SCHEMBL31062432 | 0.74 | SMARCA2 (0.39) | SMARCA2SMARCA4PBRM1CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL30368686 | 0.73 | SMARCA2 (0.39) | SMARCA2SMARCA4PBRM1CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL29008605 | 0.73 | SMARCA2 (0.39) | SMARCA2SMARCA4PBRM1CHRM2CHRM4 | |
| SCHEMBL9367057 | 0.70 | NOTUM (0.55) | SMARCA2SMARCA4PBRM1LMNAALDH1A1 | |
| SCHEMBL15896058 | 0.70 | KDM4E (0.46) | SMARCA2SMARCA4PBRM1ALDH1A1CCNE2 | |
| SCHEMBL29823001 | 0.70 | KDM4E (0.46) | SMARCA2SMARCA4PBRM1ALDH1A1CCNE2 | |
| SCHEMBL3435118 | 0.69 | KEAP1 (0.58) | SMARCA2SMARCA4PBRM1CHRM2CHRM4 | |
| SCHEMBL30783767 | 0.69 | SMARCA2 (0.47) | SMARCA2SMARCA4PBRM1CHRM2CHRM4 | |
| SCHEMBL30784053 | 0.69 | SMARCA2 (0.47) | SMARCA2SMARCA4PBRM1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693507-A | Inhibitor compounds | 奈奥芬莱有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-115996907-A | Inhibitors of MLH1 and/or PMS2 for cancer treatment | 奈奥芬莱有限公司 | 2023-04-21 | — | — | CN | claimed |
| CN-117693507-A | Inhibitor compounds | 奈奥芬莱有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115996907-A | Inhibitors of MLH1 and/or PMS2 for cancer treatment | 奈奥芬莱有限公司 | 2023-04-21 | — | — | CN | disclosed |