SCHEMBL29008680

SCHEMBL29008680

NC(=O)C(N)CSSCC(N)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 8/20 0.47
NOS1 P29475 6/20 0.47
NOS3 P29474 5/20 0.47
ARG1 P05089 1/20 0.44
ARG2 P78540 1/20 0.44
ALOX15 P16050 2/20 0.43
KMT2A Q03164 2/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
PTGS1 P23219 1/20 0.42
SLC7A11 Q9UPY5 1/20 0.42
GRIK1 P39086 2/20 0.41
GRIK2 Q13002 2/20 0.41
GRM1 Q13255 2/20 0.41
GRM2 Q14416 2/20 0.41
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 2/20 0.39
SLC7A5 Q01650 1/20 0.39
GRM8 O00222 1/20 0.39
GRM6 O15303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9703082 1.00 NOS2 (0.47) NOS2NOS1NOS3ARG1ARG2
Cystine SCHEMBL5223305 0.90 NOS2 (0.50) NOS2NOS1NOS3ARG1ARG2
Cystine SCHEMBL5223299 0.90 NOS2 (0.50) NOS2NOS1NOS3ARG1ARG2
Cystine SCHEMBL10224 0.90 PTGS1 (0.50) NOS2NOS1NOS3ARG1ARG2
SCHEMBL4922553 0.90 NOS2 (0.35) NOS2NOS1NOS3ARG1ARG2
Cystine SCHEMBL10225 0.90 PTGS1 (0.50) NOS2NOS1NOS3ARG1ARG2
Cystine SCHEMBL5018669 0.90 PTGS1 (0.50) NOS2NOS1NOS3ARG1ARG2
Cystine SCHEMBL8332360 0.90 PTGS1 (0.50) NOS2NOS1NOS3ARG1ARG2
SCHEMBL9200531 0.90 NOS2 (0.35) NOS2NOS1NOS3ARG1ARG2
Cystine SCHEMBL8332353 0.90 PTGS1 (0.50) NOS2NOS1NOS3ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113527657-B Polyethylene glycol modified cystine amide derivative, preparation and application thereof 武汉纳乐吉生命科技有限公司 2023-05-30 CN claimed
CN-110386890-B Drug-loaded nano hydrogel based on cysteamine derivatives and preparation method thereof 沈阳药科大学 2021-06-18 CN claimed
CN-121930144-A Multifunctional hair cosmetic active raw material and preparation method and application thereof 广州澳谷化妆品制造有限公司 2026-04-28 CN disclosed
CN-113527657-B Polyethylene glycol modified cystine amide derivative, preparation and application thereof 武汉纳乐吉生命科技有限公司 2023-05-30 CN disclosed
CN-113527657-B Polyethylene glycol modified cystine amide derivative, preparation and application thereof 武汉纳乐吉生命科技有限公司 2023-05-30 CN disclosed
CN-113527657-B Polyethylene glycol modified cystine amide derivative, preparation and application thereof 武汉纳乐吉生命科技有限公司 2023-05-30 CN disclosed
CN-113527657-A Polyethylene glycol modified cysteamine derivative, preparation and application thereof 武汉纳乐吉生命科技有限公司 2021-10-22 CN disclosed