Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 4/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | WNT3 | P56703 | 1/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26615251 | 1.00 | JAK1 (0.44) | JAK1JAK2TYRO3HSD17B10CYP3A4 | |
| SCHEMBL10015708 | 0.86 | HTT (0.47) | JAK1CYP3A4CYP2D6 | |
| SCHEMBL8261299 | 0.86 | HTT (0.47) | JAK1CYP3A4CYP2D6 | |
| SCHEMBL14233304 | 0.86 | HPGD (0.48) | — | |
| SCHEMBL15014605 | 0.85 | ALDH1A1 (0.43) | JAK1JAK2HSD17B10CYP3A4CYP2D6 | |
| SCHEMBL15014480 | 0.85 | ALDH1A1 (0.43) | JAK1JAK2HSD17B10CYP3A4CYP2D6 | |
| SCHEMBL8194282 | 0.83 | HTT (0.53) | — | |
| SCHEMBL20199815 | 0.83 | HTT (0.53) | — | |
| SCHEMBL19369982 | 0.83 | HTT (0.53) | — | |
| SCHEMBL26728466 | 0.82 | HSD17B10 (0.57) | JAK1JAK2HSD17B10WNT3SFRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115835908-A | Bicyclic heterocycles as FGFR inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | claimed |
| CN-115835908-A | Bicyclic heterocycles as FGFR inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | disclosed |