SCHEMBL29009015

SCHEMBL29009015

CC(C)(C)c1cc(C2(c3ccc(OCCO)c(C(C)(C)C)c3)c3ccccc3-c3ccccc32)ccc1OCCO.CCC(C)c1cc(C2(c3ccc(OCCO)c(C(C)CC)c3)c3ccccc3-c3ccccc32)ccc1OCCO

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
PDK2 Q15119 4/20 0.34
KDM4E B2RXH2 8/20 0.34
ALDH1A1 P00352 5/20 0.34
TDP1 Q9NUW8 1/20 0.34
ATM Q13315 1/20 0.33
RARA P10276 1/20 0.32
RARB P10826 1/20 0.32
RARG P13631 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPK1 P28482 2/20 0.31
GAA P10253 1/20 0.31
HTT P42858 1/20 0.31
PKM P14618 1/20 0.31
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL384159 0.92 ESR1 (0.40) ESR1ESR2PDK2KDM4EALDH1A1
SCHEMBL29407805 0.88 ESR1 (0.43) ESR1ESR2PDK2KDM4EALDH1A1
SCHEMBL812773 0.88 ESR1 (0.43) ESR1ESR2PDK2KDM4EALDH1A1
SCHEMBL29112874 0.83 ESR1 (0.35) ESR1ESR2PDK2KDM4EALDH1A1
SCHEMBL382295 0.81 ESR1 (0.43) ESR1ESR2PDK2KDM4EALDH1A1
SCHEMBL29445690 0.81 ESR1 (0.43) ESR1ESR2PDK2KDM4EALDH1A1
SCHEMBL9279728 0.80 KDM4E (0.37) ESR1ESR2PDK2KDM4EALDH1A1
SCHEMBL20718779 0.80 ESR1 (0.41) ESR1ESR2PDK2KDM4EALDH1A1
SCHEMBL383004 0.78 PDK2 (0.38) ESR1ESR2PDK2KDM4EATM
SCHEMBL30366005 0.78 PDK2 (0.38) ESR1ESR2PDK2KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116621678-A Compound, resin, polycarbonate resin, and optical molded body 三井化学株式会社 2023-08-22 CN disclosed
CN-114787116-B Compound, resin, polycarbonate resin, and optical molded body 三井化学株式会社 2023-06-02 CN disclosed