Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TACR3 | P29371 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009155 | 0.86 | CNR2 (0.45) | TACR3KMT2AMEN1 | |
| SCHEMBL29009159 | 0.86 | CNR2 (0.47) | TACR3ATMGPR88 | |
| SCHEMBL29009166 | 0.86 | ALDH1A1 (0.46) | KMT2AMEN1 | |
| SCHEMBL4242518 | 0.86 | KMT2A (0.56) | TACR3KMT2AATMMEN1GPR88 | |
| SCHEMBL10316570 | 0.80 | TACR3 (0.50) | ESR1ESR2TACR3KMT2AATM | |
| SCHEMBL30079260 | 0.80 | ESR1 (0.50) | ESR1ESR2TACR3KMT2AMEN1 | |
| SCHEMBL13749425 | 0.79 | TACR3 (0.49) | ESR1ESR2TACR3KMT2AMEN1 | |
| SCHEMBL10210691 | 0.76 | ESR1 (0.53) | ESR1ESR2TACR3KMT2AMEN1 | |
| SCHEMBL12379279 | 0.76 | ESR1 (0.53) | ESR1ESR2TACR3KMT2AMEN1 | |
| SCHEMBL13919960 | 0.76 | ESR1 (0.53) | ESR1ESR2TACR3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |