Methane

Methane

SCHEMBL29009208

C.Oc1cccc(-c2ccco2)c1O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.44
ALOX15 P16050 4/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 3/20 0.44
MAPT P10636 3/20 0.44
CASP1 P29466 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
RECQL P46063 3/20 0.42
HSD17B10 Q99714 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
LMNA P02545 2/20 0.42
ADAMTS4 O75173 1/20 0.42
EGFR P00533 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
FYN P06241 1/20 0.42
MMP2 P08253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32665680 0.81 MEN1 (0.56) HPGDALOX15MEN1KMT2AALDH1A1
SCHEMBL8658064 0.81 MEN1 (0.56) HPGDALOX15MEN1KMT2AALDH1A1
SCHEMBL13030880 0.78 CFTR (0.43) HPGDALOX15MEN1KMT2AALDH1A1
SCHEMBL1435465 0.74 PTPN1 (0.61) HPGDMEN1KMT2AALDH1A1KDM4E
SCHEMBL12477621 0.74 HPGD (0.41) HPGDALOX15MEN1KMT2AALDH1A1
SCHEMBL28754631 0.74 MEN1 (0.45) HPGDALOX15MEN1KMT2AALDH1A1
SCHEMBL6068023 0.74 ALDH1A1 (0.44) HPGDALOX15MEN1KMT2AALDH1A1
SCHEMBL26259566 0.73 POLB (0.48) HPGDALOX15MEN1KMT2AALDH1A1
SCHEMBL29453072 0.72 ALDH1A1 (0.69) HPGDALOX15MEN1KMT2AALDH1A1
SCHEMBL337585 0.72 ALDH1A1 (0.69) HPGDALOX15MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974859-A Furyl glycidyl ether and preparation method and application thereof 南京林业大学 2023-04-18 CN disclosed