Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30382687 | 0.86 | PDPK1 (0.47) | PDPK1CHEK1FGFR1FLT1FLT3 | |
| SCHEMBL29009543 | 0.86 | PDPK1 (0.47) | PDPK1CHEK1FGFR1FLT1FLT3 | |
| SCHEMBL29009523 | 0.83 | PDPK1 (0.49) | PDPK1CHEK1FGFR1FLT1FLT3 | |
| SCHEMBL30382380 | 0.83 | PDPK1 (0.49) | PDPK1CHEK1FGFR1FLT1FLT3 | |
| SCHEMBL30382244 | 0.82 | PDPK1 (0.42) | PDPK1CHEK1FGFR1FLT1FLT3 | |
| SCHEMBL29009491 | 0.82 | PDPK1 (0.42) | PDPK1CHEK1FGFR1FLT1FLT3 | |
| SCHEMBL29009547 | 0.82 | PDPK1 (0.72) | PDPK1FGFR1FLT1FLT3 | |
| SCHEMBL29009542 | 0.81 | PDPK1 (0.60) | PDPK1CHEK1FGFR1FLT1FLT3 | |
| SCHEMBL30381750 | 0.81 | PDPK1 (0.60) | PDPK1CHEK1FGFR1FLT1FLT3 | |
| SCHEMBL29009540 | 0.79 | PDPK1 (0.59) | PDPK1CHEK1FGFR1FLT3MAP2K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | claimed |
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | disclosed |