Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 10/20 | 0.62 |
| ▸ | FLT1 | P17948 | 6/20 | 0.62 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 5/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.53 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.53 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.53 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 3/20 | 0.50 |
| ▸ | BCR | P11274 | 3/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CCND3 | P30281 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30382435 | 1.00 | FGFR1 (0.62) | FGFR1FLT1FLT3PDPK1KDR | |
| SCHEMBL30382123 | 0.91 | PDPK1 (0.66) | FGFR1FLT1FLT3PDPK1 | |
| SCHEMBL29009554 | 0.91 | PDPK1 (0.66) | FGFR1FLT1FLT3PDPK1 | |
| SCHEMBL29009524 | 0.88 | FGFR1 (0.56) | FGFR1FLT1FLT3PDPK1KDR | |
| SCHEMBL30382361 | 0.88 | FGFR1 (0.56) | FGFR1FLT1FLT3PDPK1KDR | |
| SCHEMBL3535495 | 0.86 | FGFR1 (0.62) | FGFR1FLT1FLT3PDPK1KDR | |
| SCHEMBL3540208 | 0.86 | FGFR1 (0.67) | FGFR1FLT1FLT3PDPK1KDR | |
| SCHEMBL29009501 | 0.85 | FGFR1 (0.62) | FGFR1FLT1FLT3PDPK1KDR | |
| SCHEMBL30382103 | 0.85 | FGFR1 (0.62) | FGFR1FLT1FLT3PDPK1KDR | |
| SCHEMBL3535712 | 0.83 | FGFR1 (0.58) | FGFR1FLT1FLT3PDPK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | claimed |
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | disclosed |