SCHEMBL29009554

SCHEMBL29009554

C=CS(=O)(=O)Nc1ccc2[nH]nc(-c3nc4ccc(N5CCOCC5)cc4[nH]3)c2c1

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 3/20 0.66
FGFR1 P11362 1/20 0.62
FLT1 P17948 1/20 0.62
FLT3 P36888 16/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382123 1.00 PDPK1 (0.66) PDPK1FGFR1FLT1FLT3
SCHEMBL29009498 0.91 FGFR1 (0.62) PDPK1FGFR1FLT1FLT3
SCHEMBL30382435 0.91 FGFR1 (0.62) PDPK1FGFR1FLT1FLT3
SCHEMBL29009538 0.88 FGFR1 (0.55) PDPK1FGFR1FLT1FLT3
SCHEMBL30382429 0.88 FGFR1 (0.55) PDPK1FGFR1FLT1FLT3
SCHEMBL31006222 0.84 PDPK1 (0.76) PDPK1FGFR1FLT1FLT3
SCHEMBL29009497 0.84 PDPK1 (0.76) PDPK1FGFR1FLT1FLT3
SCHEMBL30382285 0.82 PDPK1 (0.63) PDPK1FGFR1FLT1FLT3
SCHEMBL29009502 0.82 PDPK1 (0.63) PDPK1FGFR1FLT1FLT3
SCHEMBL29009505 0.82 MAPK1 (0.59) PDPK1FGFR1FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217551-A Substituted indazole or azaindazole compounds and application thereof 河南中医药大学 2023-06-06 CN claimed
CN-116217551-A Substituted indazole or azaindazole compounds and application thereof 河南中医药大学 2023-06-06 CN disclosed