Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 18/20 | 0.59 |
| ▸ | MTOR | P42345 | 14/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.59 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.59 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.59 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.59 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.40 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.40 |
| ▸ | RICTOR | Q6R327 | 2/20 | 0.40 |
| ▸ | MAPKAP1 | Q9BPZ7 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29183999 | 0.85 | PIK3CA (0.51) | PIK3CAMTORPIK3CBPIK3R1PIK3CD | |
| SCHEMBL29009711 | 0.84 | MTOR (0.59) | PIK3CAMTORPIK3CBPIK3R1PIK3CD | |
| SCHEMBL29009703 | 0.84 | PIK3CA (0.68) | PIK3CAMTORPIK3CBPIK3R1PIK3CD | |
| SCHEMBL1311311 | 0.82 | PIK3CA (0.87) | PIK3CAMTORPIK3CBPIK3R1PIK3CD | |
| SCHEMBL30186906 | 0.82 | PIK3CA (0.87) | PIK3CAMTORPIK3CBPIK3R1PIK3CD | |
| SCHEMBL29183810 | 0.77 | PIK3CA (0.54) | PIK3CAMTORPIK3R1PIK3CDPIK3CG | |
| SCHEMBL29879988 | 0.75 | PIK3CA (1.00) | PIK3CAMTORPIK3CBPIK3R1PIK3CD | |
| SCHEMBL1309466 | 0.75 | PIK3CA (1.00) | PIK3CAMTORPIK3CBPIK3R1PIK3CD | |
| SCHEMBL18117888 | 0.73 | PIK3CA (0.91) | PIK3CAMTORPIK3CBPIK3R1PIK3CD | |
| SCHEMBL18117918 | 0.72 | PIK3CA (0.68) | PIK3CAMTORPIK3CBPIK3R1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109414415-B | Treatment of skin lesions | 拓客股份有限公司 | 2023-05-02 | — | — | CN | disclosed |