Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 19/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 18/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.59 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.59 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.59 |
| ▸ | PRKDC | P78527 | 2/20 | 0.59 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.59 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.59 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.59 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.59 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009702 | 0.84 | PIK3CA (0.74) | MTORPIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL29009704 | 0.84 | PIK3CA (0.59) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| SCHEMBL1309194 | 0.82 | PIK3CA (0.87) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| SCHEMBL29183999 | 0.80 | PIK3CA (0.51) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| SCHEMBL29183810 | 0.80 | PIK3CA (0.54) | MTORPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL28720167 | 0.79 | PIK3CA (0.75) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| Bimiralisib SCHEMBL1309049 | 0.75 | PIK3CA (1.00) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| Bimiralisib SCHEMBL29352266 | 0.75 | PIK3CA (1.00) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| Bimiralisib SCHEMBL29644978 | 0.74 | PIK3CA (0.98) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| Bimiralisib SCHEMBL18428577 | 0.74 | PIK3CA (0.98) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777042-A | Triazine hydroxamic acid derivative and preparation method and application thereof | 长沙医学院 | 2024-03-29 | — | — | CN | disclosed |
| CN-109414415-B | Treatment of skin lesions | 拓客股份有限公司 | 2023-05-02 | — | — | CN | disclosed |