SCHEMBL29009787

SCHEMBL29009787

O=C(O)[C@@H](F)Cc1cc(F)cc(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.40
PPARA Q07869 3/20 0.40
DAO P14920 2/20 0.40
MDM2 Q00987 1/20 0.39
METAP2 P50579 6/20 0.38
MME P08473 2/20 0.37
FFAR4 Q5NUL3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29009791 1.00 PPARG (0.40) PPARGPPARADAOMDM2METAP2
SCHEMBL30428012 1.00 PPARG (0.40) PPARGPPARADAOMDM2METAP2
SCHEMBL845968 0.81 SLC7A5 (0.49)
SCHEMBL845967 0.81 SLC7A5 (0.49)
SCHEMBL25216614 0.79 PPARG (0.37) PPARGPPARAMDM2FFAR4
SCHEMBL156863 0.74 FFAR4 (0.43) DAOMETAP2FFAR4
SCHEMBL25210806 0.74 PPARG (0.54) PPARGPPARA
SCHEMBL22029959 0.74 SLC1A1 (0.62) PPARGPPARAMDM2
SCHEMBL12450288 0.72 PNMT (0.37) DAOMDM2METAP2
SCHEMBL3930469 0.71 FFAR4 (0.47) MMEFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed