Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25408725 | 0.81 | GAA (0.44) | CES1CES2GAACNR2CYP1A2 | |
| SCHEMBL6533964 | 0.79 | GAA (0.43) | CES1CES2GAACNR2CYP1A2 | |
| SCHEMBL7724344 | 0.71 | CES2 (0.48) | CES1CES2GAAALDH1A1ALOX15 | |
| SCHEMBL19458984 | 0.71 | CNR2 (0.50) | CES1CES2GAAALDH1A1ALOX15 | |
| SCHEMBL30015486 | 0.70 | CES2 (0.41) | CES1CES2GAAALDH1A1ALOX15 | |
| SCHEMBL20213648 | 0.70 | CES2 (0.41) | CES1CES2GAAALDH1A1ALOX15 | |
| SCHEMBL29362410 | 0.69 | CES2 (0.61) | CES1CES2GAAALDH1A1ALOX15 | |
| SCHEMBL1285812 | 0.69 | CES2 (0.47) | CES1CES2GAAALDH1A1ALOX15 | |
| SCHEMBL1885454 | 0.69 | CES2 (0.47) | CES1CES2GAAALDH1A1ALOX15 | |
| SCHEMBL27819947 | 0.69 | GAA (0.50) | CES1CES2GAAALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209433-A | Small molecule albumin binding agents | 俄勒冈健康科学大学 | 2023-06-02 | — | — | CN | disclosed |