SCHEMBL29010065

SCHEMBL29010065

O=C(O)C(c1ccccc1)(C(F)F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.42
PTPN1 P18031 1/20 0.41
CYP2D6 P10635 1/20 0.40
ALDH1A1 P00352 5/20 0.39
TSHR P16473 2/20 0.39
MAPT P10636 4/20 0.38
S1PR4 O95977 2/20 0.38
LMNA P02545 2/20 0.38
S1PR1 P21453 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
CES1 P23141 2/20 0.38
KMT2A Q03164 2/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA5A P35218 1/20 0.35
CA9 Q16790 1/20 0.35
KCNN4 O15554 3/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666956 0.79 CYP1A2 (0.49) CYP1A2PTPN1CYP2D6MAPTKMT2A
SCHEMBL28147722 0.75 CYP1A2 (0.45) CYP1A2PTPN1CYP2D6ALDH1A1TSHR
SCHEMBL31181862 0.72 ALDH1A1 (0.44) CYP1A2PTPN1CYP2D6ALDH1A1TSHR
SCHEMBL14670850 0.72 CYP2D6 (0.49) CYP1A2PTPN1CYP2D6MAPTLMNA
SCHEMBL29009831 0.70 CYP1A2 (0.48) CYP1A2PTPN1CYP2D6ALDH1A1TSHR
SCHEMBL2429483 0.70 CYP1A2 (0.48) CYP1A2PTPN1CYP2D6ALDH1A1TSHR
SCHEMBL27785770 0.70 CYP1A2 (0.48) CYP1A2PTPN1CYP2D6ALDH1A1TSHR
SCHEMBL4591516 0.70 CYP1A2 (0.48) CYP1A2PTPN1CYP2D6ALDH1A1TSHR
SCHEMBL4660655 0.70 CYP1A2 (0.48) CYP1A2PTPN1CYP2D6ALDH1A1TSHR
SCHEMBL27842812 0.69 CYP1A2 (0.43) CYP1A2PTPN1CYP2D6ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed