SCHEMBL29010075

SCHEMBL29010075

O=C(O)C(F)(c1ccccc1)C(F)(F)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.45
PTPN1 P18031 2/20 0.43
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
CES1 P23141 2/20 0.40
CYP2D6 P10635 1/20 0.38
THRB P10828 1/20 0.38
MAPT P10636 3/20 0.38
KMT2A Q03164 2/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
KCNN4 O15554 3/20 0.37
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
S1PR4 O95977 1/20 0.37
LMNA P02545 1/20 0.37
S1PR1 P21453 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29009831 0.86 CYP1A2 (0.48) CYP1A2PTPN1ALDH1A1TSHRCES1
SCHEMBL4660655 0.86 CYP1A2 (0.48) CYP1A2PTPN1ALDH1A1TSHRCES1
SCHEMBL31181863 0.83 MAPT (0.44) CYP1A2PTPN1ALDH1A1TSHRCES1
SCHEMBL9596292 0.79 CYP2C19 (0.39) CYP1A2PTPN1ALDH1A1TSHRCES1
SCHEMBL28059707 0.78 MAPT (0.47) CYP1A2PTPN1ALDH1A1TSHRCES1
SCHEMBL583794 0.77 CYP1A2 (0.43) CYP1A2PTPN1ALDH1A1TSHRCES1
SCHEMBL31181862 0.75 ALDH1A1 (0.44) CYP1A2PTPN1ALDH1A1TSHRCES1
SCHEMBL1667160 0.75 CYP1A2 (0.48) CYP1A2PTPN1ALDH1A1TSHRCYP2D6
SCHEMBL3822241 0.75 ALDH1A1 (0.45) CYP1A2ALDH1A1MAPTKMT2ACA1
SCHEMBL2429483 0.73 CYP1A2 (0.48) CYP1A2PTPN1ALDH1A1TSHRCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed