Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401825 | 0.98 | NAAA (0.41) | NAAAEPHX1HTTCYP19A1SMN1; SMN2 | |
| SCHEMBL5158628 | 0.91 | NAAA (0.41) | NAAAEPHX1HTTCYP19A1SMN1; SMN2 | |
| SCHEMBL9009690 | 0.83 | NAAA (0.57) | NAAAEPHX1HTTCYP2C19ALDH1A1 | |
| SCHEMBL29117609 | 0.83 | NAAA (0.57) | NAAAEPHX1HTTCYP2C19ALDH1A1 | |
| SCHEMBL5075294 | 0.81 | NAAA (0.64) | NAAAEPHX1HTTALDH1A1MEN1 | |
| SCHEMBL2340701 | 0.81 | EPHX1 (0.42) | NAAAEPHX1HTTCYP19A1SMN1; SMN2 | |
| SCHEMBL6433418 | 0.80 | NAAA (0.67) | NAAAEPHX1HTTALDH1A1 | |
| SCHEMBL9468402 | 0.80 | NAAA (0.67) | NAAAEPHX1HTTALDH1A1 | |
| SCHEMBL28473788 | 0.80 | NAAA (0.63) | NAAAEPHX1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2045276 | 0.80 | NAAA (0.41) | NAAAEPHX1HTTCYP19A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234585-A | Microtubule-associated protein TAU (MAPT) iRNA agent compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2023-06-06 | — | — | CN | disclosed |