Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29163806 | 0.82 | LMNA (0.50) | NPC1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2471464 | 0.82 | LMNA (0.50) | NPC1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Acetic Acid SCHEMBL27797755 | 0.79 | SCN1A (0.47) | KMT2ASMN1; SMN2ALDH1A1GAALMNA | |
| Salicylic Acid SCHEMBL28463606 | 0.76 | KDM4E (0.48) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1771830 | 0.75 | NPC1 (0.61) | NPC1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11772453 | 0.74 | NPC1 (0.53) | NPC1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28882905 | 0.71 | NPC1 (0.53) | NPC1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL598345 | 0.71 | MEN1 (0.69) | NPC1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL18461334 | 0.71 | HPGD (0.51) | NPC1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL3805681 | 0.70 | SCN1A (0.39) | NPC1KMT2AALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105820107-B | Prodrug of non-steroidal anti-inflammatory drug with rapid skin and biological membrane penetration speed and novel medical application thereof | 泰飞尔公司 | 2022-09-09 | — | — | CN | disclosed |