Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 15/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | LDLR | P01130 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2902012 | 0.87 | LMNA (0.54) | MAPK14MAPK11CTDSP1TDP1 | |
| SCHEMBL239703 | 0.83 | NPC1 (0.56) | MAPK14MAPK11 | |
| SCHEMBL242627 | 0.82 | CTDSP1 (0.58) | MAPK14MAPK11CTDSP1TDP1 | |
| SCHEMBL2904915 | 0.81 | MAPK14 (0.52) | MAPK14MAPK11CTDSP1TDP1MAPK13 | |
| SCHEMBL244106 | 0.80 | MAPK14 (0.55) | MAPK14MAPK11MAPK13MAPK12SMO | |
| SCHEMBL243749 | 0.80 | MAPK14 (0.56) | MAPK14MAPK11MAPK13MAPK12SMO | |
| Hydrochloric Acid SCHEMBL242063 | 0.79 | MAPK14 (0.54) | MAPK14MAPK11MAPK13MAPK12SMO | |
| Bromide SCHEMBL243303 | 0.79 | MAPK14 (0.54) | MAPK14MAPK11MAPK13MAPK12SMO | |
| SCHEMBL2901479 | 0.79 | MAPK14 (0.52) | MAPK14MAPK11SMO | |
| SCHEMBL1901158 | 0.79 | MAPK11 (0.55) | MAPK14MAPK11MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699766-B1 | AMIDE DERIVATIVES BEARING A CYCLOPROPYLAMINOACARBONYL SUBSTITUENT USEFUL AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-11 | — | — | EP | claimed |