Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 13/20 | 0.52 |
| ▸ | CES1 | P23141 | 12/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10393740 | 1.00 | CES2 (0.52) | CES2CES1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16973952 | 0.85 | CES2 (0.52) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL995359 | 0.81 | MAPT (0.59) | CES2CES1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11723691 | 0.81 | MAPT (0.59) | CES2CES1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27662613 | 0.80 | CES2 (0.43) | CES2CES1CYP1A2CYP3A4CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL28224094 | 0.80 | EP300 (0.59) | CES2CES1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7451708 | 0.80 | EP300 (0.64) | CES2CES1 | |
| SCHEMBL11560694 | 0.80 | EP300 (0.64) | CES2CES1 | |
| SCHEMBL16974008 | 0.80 | CES2 (0.61) | CES2CES1MAPTALDH1A1KMT2A | |
| SCHEMBL9540488 | 0.79 | CES2 (0.56) | CES2CES1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106192061-A | A kind of anophelifuge PBAT fiber | 福建经纬新纤科技实业有限公司 | 2016-12-07 | — | — | CN | claimed |
| US-4925969-A | MICHAEL ADDITION, ALANINE OR LYSINE DERIVATIVE REACTED WITH ETHYL BENZOYLACRYLATE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-05-15 | — | — | US | claimed |
| EP-0190687-B1 | PROCESS FOR PREPARING ETHYL-ALPHA-(1-CARBOXYETHYL)-AMINO-GAMMA-OXO-GAMMA-PHENYLBUTYRATE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-10-05 | — | — | EP | claimed |
| EP-0190687-A1 | Process for preparing ethyl-alpha-(1-carboxyethyl)-amino-gamma-oxo-gamma-phenylbutyrate | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-08-13 | — | — | EP | claimed |
| CN-114369198-B | 3-benzoyl ethyl acrylate diesel pour point depressant, diesel pour point depressant composition, preparation and application | 上海应用技术大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-114933543-A | Synthetic method of 3-cyclopropylamino-2- (2, 4-dichloro-5-fluorobenzoyl) methyl acrylate | 山东国邦药业有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-114605587-A | PMA diesel pour point depressant and preparation method and application thereof | 上海应用技术大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-107058453-A | A kind of method of biocatalytic resolution lisinopril hydride | 长兴制药股份有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106192061-A | A kind of anophelifuge PBAT fiber | 福建经纬新纤科技实业有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-105294827-A | Preparation method for enalapril maleate | CHANGZHOU PHARMACEUTICAL FACTORY | 2016-02-03 | — | — | CN | disclosed |
| EP-2481736-A1 | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases | Deciphera Pharmaceuticals, LLC. (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2148677-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYLEOPROLIFERATIVE DISEASES AND OTHER PROLIFERATIVE DISEASES | Deciphera Pharmaceuticals, LLC. (US) | 2010-02-03 | — | — | EP | disclosed |
| US-20080269267-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYLEOPROLIFIC DISEASES AND OTHER PROLIFERATIVE DISEASES | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-10-30 | — | — | US | disclosed |
| WO-2008131276-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYLEOPROLIFERATIVE DISEASES AND OTHER PROLIFERATIVE DISEASES | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-10-30 | — | — | WO | disclosed |
| WO-1998001511-A1 | REACTION PROCUCTS OF LYOTROPIC LIQUID CRYSTAL SALT COMPLEXES | ELLIOTT STANLEY B (US) | 1998-01-15 | — | — | WO | disclosed |
| US-4925969-A | MICHAEL ADDITION, ALANINE OR LYSINE DERIVATIVE REACTED WITH ETHYL BENZOYLACRYLATE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0190687-B1 | PROCESS FOR PREPARING ETHYL-ALPHA-(1-CARBOXYETHYL)-AMINO-GAMMA-OXO-GAMMA-PHENYLBUTYRATE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-10-05 | — | — | EP | disclosed |
| EP-0190687-A1 | Process for preparing ethyl-alpha-(1-carboxyethyl)-amino-gamma-oxo-gamma-phenylbutyrate | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-08-13 | — | — | EP | disclosed |
| EP-0190687-A1 | Process for preparing ethyl-alpha-(1-carboxyethyl)-amino-gamma-oxo-gamma-phenylbutyrate | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269267-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF MYLEOPROLIFIC DISEASES AND OTHER PROLIFERATIVE DISEASES | BRAF, RET, KIT | CES2 2763/4885CES1 1692/4885CYP1A2 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.