Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 3/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25335312 | 0.87 | IDH1 (0.39) | FFAR4CNR1IDH1 | |
| SCHEMBL30135967 | 0.85 | CTSL (0.39) | FFAR4CNR1IDH1CHRM4 | |
| SCHEMBL25822405 | 0.79 | FFAR4 (0.60) | FFAR4 | |
| SCHEMBL29013177 | 0.79 | FFAR4 (0.47) | FFAR4FEN1GRM5S1PR5CHRM4 | |
| SCHEMBL26126364 | 0.79 | FFAR4 (0.43) | FFAR4FEN1GRM5NPY2R | |
| SCHEMBL25031334 | 0.78 | FFAR4 (0.47) | FFAR4FEN1GRM5 | |
| SCHEMBL25333606 | 0.78 | FFAR4 (0.50) | FFAR4GRM5CHRM4 | |
| SCHEMBL29013211 | 0.78 | FFAR4 (0.39) | FFAR4FEN1GRM5RPS6KB1CNR1 | |
| SCHEMBL25935098 | 0.77 | SMPD3 (0.44) | FFAR4CNR1IDH1CHRM4 | |
| SCHEMBL29013165 | 0.77 | GRM5 (0.48) | FFAR4GRM5NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261458-B | PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116261458-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-13 | — | — | CN | disclosed |