Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30312094 | 1.00 | ASH1L (0.47) | ASH1LTGFBR1CCR1CCR8MAPK14 | |
| SCHEMBL30311908 | 0.81 | ASH1L (0.44) | ASH1LTGFBR1MAPK14SMN1; SMN2ALDH1A1 | |
| SCHEMBL29013285 | 0.81 | ASH1L (0.44) | ASH1LTGFBR1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31621265 | 0.81 | ASH1L (0.44) | ASH1LTGFBR1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30311917 | 0.81 | ASH1L (0.44) | ASH1LTGFBR1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL29013235 | 0.81 | ASH1L (0.44) | ASH1LTGFBR1MAPK14SMN1; SMN2ALDH1A1 | |
| SCHEMBL29013271 | 0.78 | PIK3CD (0.55) | ASH1LTGFBR1CCR1CCR8MAPK14 | |
| SCHEMBL29013268 | 0.78 | ASH1L (0.44) | ASH1LTGFBR1 | |
| SCHEMBL30312084 | 0.78 | ASH1L (0.47) | ASH1LTGFBR1MAPK14SMN1; SMN2ALDH1A1 | |
| SCHEMBL29013263 | 0.78 | ASH1L (0.47) | ASH1LTGFBR1MAPK14SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850263-A | 2, 7-disubstituted benzothiazole compound and application thereof | 浙江工业大学 | 2023-03-28 | — | — | CN | disclosed |