Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | PI4KA | P42356 | 3/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.38 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30312084 | 1.00 | ASH1L (0.47) | ASH1LSMN1; SMN2PIK3CDPI4KAPIK3CG | |
| SCHEMBL30312191 | 0.85 | ASH1L (0.49) | ASH1LSMN1; SMN2PIK3CDPI4KAPIK3CG | |
| SCHEMBL29013267 | 0.85 | ASH1L (0.49) | ASH1LSMN1; SMN2PIK3CDPI4KAPIK3CG | |
| SCHEMBL29013231 | 0.85 | ASH1L (0.54) | ASH1LSMN1; SMN2PIK3CDPI4KAPIK3CG | |
| SCHEMBL30311987 | 0.85 | ASH1L (0.54) | ASH1LSMN1; SMN2PIK3CDPI4KAPIK3CG | |
| SCHEMBL29013280 | 0.82 | ASH1L (0.44) | ASH1LSMN1; SMN2PIK3CDPI4KAPIK3CG | |
| SCHEMBL30311660 | 0.82 | ASH1L (0.44) | ASH1LSMN1; SMN2PIK3CDPI4KAPIK3CG | |
| SCHEMBL29013237 | 0.78 | ASH1L (0.47) | ASH1LSMN1; SMN2TGFBR1MAPK14RAB9A | |
| SCHEMBL30312094 | 0.78 | ASH1L (0.47) | ASH1LSMN1; SMN2TGFBR1MAPK14RAB9A | |
| SCHEMBL31621273 | 0.77 | CYP1A2 (0.47) | ASH1LCYP1A2CYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850263-A | 2, 7-disubstituted benzothiazole compound and application thereof | 浙江工业大学 | 2023-03-28 | — | — | CN | disclosed |