Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PI4KA | P42356 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.40 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30312191 | 1.00 | ASH1L (0.49) | ASH1LPIK3CDPI4KAPIK3CGPI4KB | |
| SCHEMBL30311987 | 0.87 | ASH1L (0.54) | ASH1LPIK3CDPI4KAPIK3CGPI4KB | |
| SCHEMBL29013231 | 0.87 | ASH1L (0.54) | ASH1LPIK3CDPI4KAPIK3CGPI4KB | |
| SCHEMBL29013263 | 0.85 | ASH1L (0.47) | ASH1LPIK3CDPI4KAPIK3CGPI4KB | |
| SCHEMBL30312084 | 0.85 | ASH1L (0.47) | ASH1LPIK3CDPI4KAPIK3CGPI4KB | |
| SCHEMBL30311660 | 0.82 | ASH1L (0.44) | ASH1LPIK3CDPI4KAPIK3CGPI4KB | |
| SCHEMBL29013280 | 0.82 | ASH1L (0.44) | ASH1LPIK3CDPI4KAPIK3CGPI4KB | |
| SCHEMBL31621273 | 0.77 | CYP1A2 (0.47) | ASH1LALDH1A1 | |
| SCHEMBL31621271 | 0.76 | ASH1L (0.40) | ASH1LPIK3CDPI4KAPIK3CGPI4KB | |
| SCHEMBL31621267 | 0.76 | ASH1L (0.42) | ASH1LPIK3CDPI4KAPIK3CGPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850263-A | 2, 7-disubstituted benzothiazole compound and application thereof | 浙江工业大学 | 2023-03-28 | — | — | CN | disclosed |