Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Hydantoin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydantoin SCHEMBL28140889 | 0.84 | CRBN (0.44) | CRBNTSHRITGB3ITGB1ITGAV | |
| Hydantoin SCHEMBL16971290 | 0.82 | CRBN (0.42) | OR51E2CRBN | |
| Hydantoin SCHEMBL2875362 | 0.80 | CRBN (0.41) | CRBNITGB3ITGB1ITGAV | |
| Hydantoin SCHEMBL27690 | 0.79 | — | — | |
| Hydantoin SCHEMBL7285865 | 0.79 | — | — | |
| Hydantoin SCHEMBL27705088 | 0.79 | CRBN (0.52) | OR51E2CRBN | |
| Hydantoin SCHEMBL27655704 | 0.78 | CRBN (0.39) | CRBNITGB3ITGB1ITGAV | |
| Hydantoin SCHEMBL10636755 | 0.78 | CRBN (0.42) | CRBN | |
| Hydantoin SCHEMBL599570 | 0.78 | CRBN (0.42) | CRBN | |
| Hydantoin SCHEMBL27932488 | 0.78 | CRBN (0.35) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217421-A | Method for recovering glycine and co-producing feed-grade calcium hydrophosphate from glycine crude crystallization mother liquor | 天宝动物营养科技股份有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-116217420-A | Method for regenerating glycine by directly producing glycine crystallization mother liquor by hydantoin method | 天宝动物营养科技股份有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-116217421-A | Method for recovering glycine and co-producing feed-grade calcium hydrophosphate from glycine crude crystallization mother liquor | 天宝动物营养科技股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116217420-A | Method for regenerating glycine by directly producing glycine crystallization mother liquor by hydantoin method | 天宝动物营养科技股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116217420-A | Method for regenerating glycine by directly producing glycine crystallization mother liquor by hydantoin method | 天宝动物营养科技股份有限公司 | 2023-06-06 | — | — | CN | disclosed |