Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.71 |
| ▸ | F3 | P13726 | 2/20 | 0.71 |
| ▸ | MAOA | P21397 | 3/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | XDH | P47989 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | P4HB | P07237 | 1/20 | 0.64 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.62 |
| ▸ | BCHE | P06276 | 2/20 | 0.62 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.62 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.62 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31463109 | 0.97 | MAOB (0.71) | MAOBF3MAOAABCG2MAPT | |
| SCHEMBL29014268 | 0.97 | MAOB (0.71) | MAOBF3MAOAABCG2MAPT | |
| SCHEMBL29014210 | 0.90 | MAOB (0.71) | MAOBMAOAABCG2MAPTBCHE | |
| SCHEMBL7058882 | 0.88 | MAOB (0.70) | MAOBF3MAOAABCG2MAPT | |
| SCHEMBL10534582 | 0.88 | ABCG2 (0.74) | MAOBF3MAOAABCG2MAPT | |
| SCHEMBL10534587 | 0.88 | ABCG2 (0.74) | MAOBF3MAOAABCG2MAPT | |
| SCHEMBL7058879 | 0.88 | MAOB (0.70) | MAOBF3MAOAABCG2MAPT | |
| SCHEMBL29014173 | 0.88 | MAOB (0.71) | MAOBMAOAABCG2BCHECYP1B1 | |
| SCHEMBL3001785 | 0.87 | MAOB (0.70) | MAOBABCG2BCHETNFRSF1ACYP1B1 | |
| SCHEMBL3003871 | 0.87 | MAOB (0.70) | MAOBABCG2BCHETNFRSF1ACYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217461-B | Chalcone derivative containing indole structure and preparation method and application thereof | 贵州大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-116217461-A | Chalcone derivative containing indole structure and preparation method and application thereof | 贵州大学 | 2023-06-06 | — | — | CN | disclosed |