SCHEMBL7058879

SCHEMBL7058879

COc1ccc(/C=C/C(=O)c2ccc(OCCCCCCO)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.70
F3 P13726 2/20 0.69
ABCG2 Q9UNQ0 2/20 0.63
MAPT P10636 4/20 0.63
MAOA P21397 3/20 0.63
XDH P47989 2/20 0.63
MEN1 O00255 2/20 0.63
ALDH1A1 P00352 2/20 0.63
KMT2A Q03164 2/20 0.63
P4HB P07237 1/20 0.63
CALM1 P0DP23 1/20 0.63
RAB9A P51151 1/20 0.63
NPC1 O15118 1/20 0.61
LMNA P02545 1/20 0.61
KEAP1 Q14145 1/20 0.61
NFE2L2 Q16236 1/20 0.61
BCHE P06276 3/20 0.60
HSPD1 P10809 1/20 0.60
TNFRSF1A P19438 1/20 0.60
HSPE1 P61604 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7058882 1.00 MAOB (0.70) MAOBF3ABCG2MAPTMAOA
SCHEMBL25191766 0.93 ABCG2 (0.67) MAOBABCG2BCHEACHE
SCHEMBL10534587 0.90 ABCG2 (0.74) MAOBF3ABCG2MAPTMAOA
SCHEMBL10534582 0.90 ABCG2 (0.74) MAOBF3ABCG2MAPTMAOA
SCHEMBL25195923 0.90 MAOB (0.70) MAOBABCG2MAPTMAOARAB9A
SCHEMBL29014180 0.88 MAOB (0.71) MAOBF3ABCG2MAPTMAOA
SCHEMBL18481042 0.88 ABCG2 (0.70) MAOBF3ABCG2BCHECYP1B1
SCHEMBL20608176 0.88 ABCG2 (0.70) MAOBF3ABCG2BCHECYP1B1
SCHEMBL25197831 0.87 MAOB (0.68) MAOBABCG2BCHETNFRSF1ACYP1B1
SCHEMBL25209362 0.87 ABCG2 (0.60) MAOBABCG2BCHECYP1B1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-20030104145-A1 Chemical adsorbent and liquid crystal alignment layer utilizing the same and liquid crystal display device utilizing the same and methods of manufacturing them MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-06-05 US disclosed
US-6495221-B1 EXTREMELY THIN AND TRANSPARENT FILM IN NANOMETER ORDER; HYDROCHALCONE DERIVATIVE SUBSTITUTED WITH A ISOCYANATOSILYL GROUP MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-12-17 US disclosed
EP-0962460-A1 CHEMISORPTIVE SUBSTANCE, ALIGNED LIQUID-CRYSTAL FILM AND LIQUID-CRYSTAL DISPLAY ELEMENT BOTH MADE BY USING THE SAME, AND PROCESSES FOR PRODUCING THESE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1999-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030104145-A1 Chemical adsorbent and liquid crystal alignment layer utilizing the same and liquid crystal display device utilizing the same and methods of manufacturing them UACA, CRYAA, CUTA MAOB 2509/4885F3 876/4885ABCG2 179/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885F3 5/4885ABCG2 1606/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885F3 11/4885ABCG2 3622/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885F3 11/4885ABCG2 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.