SCHEMBL29014453

SCHEMBL29014453

C=CC(=O)OC(=O)c1ncc[nH]1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
KMT2A Q03164 1/20 0.37
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
GLA P06280 1/20 0.34
BRAF P15056 1/20 0.32
HDAC1 Q13547 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31229951 0.83 NPC1 (0.47) NPC1RAB9AKMT2AHTTSMN1; SMN2
SCHEMBL9798095 0.81 THRB (0.45) NPC1RAB9AKMT2AHTTSMN1; SMN2
SCHEMBL11495124 0.79 NPC1 (0.42) NPC1RAB9AKMT2AHTTSMN1; SMN2
SCHEMBL9797904 0.79 TSHR (0.50) NPC1RAB9AKMT2AALDH1A1
SCHEMBL179869 0.78 NPC1 (0.44) NPC1RAB9AKMT2AHTTSMN1; SMN2
SCHEMBL1150474 0.77 NPC1 (0.43) NPC1RAB9AKMT2AHTTSMN1; SMN2
SCHEMBL262330 0.76
SCHEMBL5317101 0.76
SCHEMBL6765328 0.75 NPC1 (0.42) NPC1RAB9AKMT2AHTTSMN1; SMN2
SCHEMBL3034729 0.75 CYP3A4 (0.46) NPC1RAB9AKMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082243-A Preparation method of unsaturated hydrocarbyloxycarbonyl imidazole 苏州祺添新材料有限公司 2023-05-09 CN disclosed