Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446590 | 0.78 | HPGD (0.41) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL9421933 | 0.77 | HPGD (0.50) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL6240256 | 0.69 | — | — | |
| SCHEMBL28998797 | 0.69 | MAPT (0.41) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL10516152 | 0.69 | HPGD (0.41) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL7557341 | 0.69 | MAPT (0.41) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL28902312 | 0.68 | CYP2D6 (0.44) | HSD17B10ALDH1A1MAOAMAOBLMNA | |
| SCHEMBL25898771 | 0.68 | MAPT (0.36) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL7552481 | 0.67 | APP (0.52) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL2077303 | 0.66 | HPGD (0.50) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082296-B | Method for preparing 3-halogenated benzothiophene compound by monopersulfate catalysis method | 浙江医药股份有限公司新昌制药厂 | 2024-10-29 | — | — | CN | disclosed |
| CN-116082296-A | Method for preparing 3-halogenated benzothiophene compound by potassium monopersulfate catalysis method | 浙江医药股份有限公司新昌制药厂 | 2023-05-09 | — | — | CN | disclosed |