Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421933 | 0.83 | HPGD (0.50) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL29014462 | 0.78 | MAPT (0.36) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL2077303 | 0.77 | HPGD (0.50) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL31299839 | 0.77 | CYP3A4 (0.48) | MAPTHSD17B10ALDH1A1MAPK1TSHR | |
| SCHEMBL25767482 | 0.77 | ACHE (0.40) | MAPTALDH1A1ACHE | |
| SCHEMBL28998797 | 0.74 | MAPT (0.41) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL7557341 | 0.74 | MAPT (0.41) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL10516152 | 0.74 | HPGD (0.41) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL25898771 | 0.73 | MAPT (0.36) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL7552481 | 0.72 | APP (0.52) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105013535-B | A kind of catalyst and its synthetic method for preparing asymmetric conjugation diine hydrocarbon compound | 湖南大学 | 2018-02-02 | — | — | CN | claimed |
| CN-105013535-A | Catalyst for preparing asymmetric conjugated dialkyne compound and synthesis method therefor | UNIV HUNAN | 2015-11-04 | — | — | CN | claimed |
| EP-0543919-B1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS IN THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF CNS DISEASES | SEARLE & CO (US) | 1996-04-10 | — | — | EP | claimed |
| US-4559082-A | THIOCARBAMATES WITH UNSATURATED ARYL SULFIDES, SULFOXIDES OR SULFONES | STAUFFER CHEMICAL CO. (US) | 1985-12-17 | — | — | US | claimed |
| CN-122011069-A | Antitumor 1,2, 3-triazole-alpha-L-threose nucleoside phosphonate analogue and preparation method and application thereof | 河南警察学院 | 2026-05-12 | — | — | CN | disclosed |
| US-11377427-B2 | Triazoles for regulating intracellular calcium homeostasis | UNIVERSIDAD DEL PAIS VASCO (ES) | 2022-07-05 | — | — | US | disclosed |
| EP-3466933-B1 | TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS | UNIV DEL PAIS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (ES) | 2020-12-02 | — | — | EP | disclosed |
| US-20200317625-A1 | TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS | UNIVERSIDAD DEL PAIS VASCO (ES) | 2020-10-08 | — | — | US | disclosed |
| CN-108178736-B | Synthetic method for preparing alpha-vinyl azide compounds in large scale | 东北师范大学 | 2020-09-15 | — | — | CN | disclosed |
| EP-3466933-A1 | TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS | Universidad del Pais Vasco (ES) | 2019-04-10 | — | — | EP | disclosed |
| CN-105013535-B | A kind of catalyst and its synthetic method for preparing asymmetric conjugation diine hydrocarbon compound | 湖南大学 | 2018-02-02 | — | — | CN | disclosed |
| CN-107486140-A | Attapulgite adsorbing material for solidifying chromium in river bottom mud and preparation method thereof | 北京清水润土环保科技有限公司 | 2017-12-19 | — | — | CN | disclosed |
| CN-105013535-A | Catalyst for preparing asymmetric conjugated dialkyne compound and synthesis method therefor | UNIV HUNAN | 2015-11-04 | — | — | CN | disclosed |
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |
| US-4559082-A | THIOCARBAMATES WITH UNSATURATED ARYL SULFIDES, SULFOXIDES OR SULFONES | STAUFFER CHEMICAL CO. (US) | 1985-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377427-B2 | Triazoles for regulating intracellular calcium homeostasis | RYR1, ATP2A3, RYR2 | HPGD 2911/4885MAPT 1079/4885SMN1; SMN2 1129/4885 |
| US-20200317625-A1 | TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS | RYR1, ATP2A3, RYR2 | HPGD 2911/4885MAPT 1079/4885SMN1; SMN2 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.