Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30502273 | 1.00 | SCN8A (0.45) | SCN8ADRD2SRD5A2SLC5A1GAA | |
| SCHEMBL24124428 | 1.00 | SCN8A (0.45) | SCN8ADRD2SRD5A2SLC5A1GAA | |
| SCHEMBL29014700 | 1.00 | SCN8A (0.45) | SCN8ADRD2SRD5A2SLC5A1GAA | |
| SCHEMBL29014704 | 1.00 | SCN8A (0.45) | SCN8ADRD2SRD5A2SLC5A1GAA | |
| SCHEMBL29014749 | 1.00 | SCN8A (0.45) | SCN8ADRD2SRD5A2SLC5A1GAA | |
| SCHEMBL24124567 | 0.84 | ALDH1A1 (0.45) | SCN8ADRD2SRD5A2CACNA2D1CACNA1B | |
| SCHEMBL30376333 | 0.84 | ALDH1A1 (0.45) | SCN8ADRD2SRD5A2CACNA2D1CACNA1B | |
| SCHEMBL24124354 | 0.82 | SCN8A (0.66) | SCN8ASRD5A2SLC5A1CACNA2D1CACNA1B | |
| SCHEMBL24124356 | 0.82 | SCN8A (0.66) | SCN8ASRD5A2SLC5A1CACNA2D1CACNA1B | |
| SCHEMBL30376130 | 0.82 | SCN8A (0.66) | SCN8ASRD5A2SLC5A1CACNA2D1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116056697-A | 2-oxo-oxazolidine-5-carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2023-05-02 | — | — | CN | claimed |
| CN-116056697-A | 2-oxo-oxazolidine-5-carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2023-05-02 | — | — | CN | disclosed |