SCHEMBL29015162

SCHEMBL29015162

COc1cc(C)nc2c(O)cccc12.[AlH3]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 1/20 0.53
METAP2 P50579 1/20 0.46
KDM4E B2RXH2 3/20 0.45
GAA P10253 2/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 4/20 0.44
TP53 P04637 2/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP1A2 P05177 1/20 0.43
PARP1 P09874 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29555308 0.98 CRHR1 (0.55) CRHR1METAP2KDM4EGAANPC1
SCHEMBL2875528 0.98 CRHR1 (0.55) CRHR1METAP2KDM4EGAANPC1
SCHEMBL30401658 0.97 CRHR1 (0.53) CRHR1METAP2KDM4EGAANPC1
SCHEMBL26766431 0.83 CRHR1 (0.58) CRHR1KDM4EGAANPC1POLB
SCHEMBL6644825 0.81 MAPT (0.46) CRHR1METAP2KDM4EGAANPC1
SCHEMBL6643616 0.81 KDM4E (0.52) CRHR1METAP2KDM4ENPC1POLB
SCHEMBL6643288 0.81 KDM4E (0.49) CRHR1METAP2KDM4EGAANPC1
SCHEMBL7748595 0.80 ABCB1 (0.44) CRHR1KDM4EMAPTLMNAPDE10A
SCHEMBL27551420 0.80 KDM4E (0.61) CRHR1METAP2KDM4EGAAMAPT
SCHEMBL28273809 0.80 KDM4E (0.61) CRHR1METAP2KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111936505-B Tertiary alkyl-substituted polycyclic aromatic compounds and uses thereof 学校法人关西学院 2024-07-02 CN disclosed
CN-118027048-A Nitrogen-containing heteropolycyclic compound, material, element, display device, and lighting device 爱思开新材料捷恩智株式会社 2024-05-14 CN disclosed
CN-113412265-B Polycyclic aromatic compounds 学校法人关西学院 2024-05-03 CN disclosed
CN-113013366-B Organic electroluminescent element, display device, lighting device, and anthracene compound 学校法人关西学院 2024-03-26 CN disclosed
CN-111527094-B Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-03-26 CN disclosed
CN-117327108-A Polycyclic aromatic compound, process for producing the same, material, light-emitting element, display device, lighting device, and compound 学校法人关西学院 2024-01-02 CN disclosed
CN-116997557-A Polycyclic aromatic compound and organic electroluminescent element 学校法人关西学院 2023-11-03 CN disclosed
CN-116987108-A Polycyclic aromatic compound, material for organic element, composition for forming light-emitting layer, organic electroluminescent element, and device 学校法人关西学院 2023-11-03 CN disclosed
CN-116888132-A Polycyclic aromatic compounds 学校法人关西学院 2023-10-13 CN disclosed
CN-111212844-B Dimer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-08-25 CN disclosed
CN-110719914-B Polycyclic aromatic compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-07-28 CN disclosed
CN-111357128-B Material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-07-11 CN disclosed
CN-116096835-A Polycyclic aromatic compounds 学校法人关西学院 2023-05-09 CN disclosed
CN-116096201-A Delayed fluorescence organic electroluminescent element, display device and lighting device 学校法人关西学院 2023-05-09 CN disclosed